Tadalafil, 6 tabs per 20 mg
Tadalafil is one of the more popular erectile dysfunction (ED) medications on the market and is most commonly associated with the brand name Cialis. Released by GlaxoSmithKline in 2003 and now owned by Eli Lilly, Cialis is very similar to the popular ED medication Viagra with the biggest difference being the drug’s active life. Cialis will produce erections for 36-48 hours from one single dose where Viagra is limited to 4-6 hours from one single dose. Cialis is also prescribed for the treatment of BPH (Benign Prostatic Hyperplasia), which refers to an enlarged prostate that results in difficulty or frequent urination.
Tadalafil belongs to the class of drugs known as phosphodiesterase type 5 inhibitors (PED5 Inhibitor). The treatment of ED is the drug’s primary purpose with the treatment of BPH being a secondary benefit discovered years after the drug was released. Cialis (name brand) as well as any generic brand of Tadalafil carries an active half-life of approximately 18 hours. Due to the long half-life and even longer active life, Cialis is commonly referred to as “The Weekend Pill”. The PED5 does not produce erections on its own, sexual stimulation must still exist, but it will ensure an erection can be maintained if blood flow issues were preventing it before.
Cialis, as with other common PED5 inhibitors functions by increasing the blood flow to the penis. The penile arteries are relaxed and nitric oxide is released via the nerves to the endothelial cells into the penis. This action promotes the synthesis of cGMP thereby resulting in a fuller, stronger and longer lasting erection. Those who suffer from ED may do so in a way that prevents them from obtaining an erection or they may be able to obtain one but unable to maintain it due to poor penile blood flow. Cialis will remedy such blood flow issues.
The effects of Cialis (positive effects) are very straightforward and primarily surround ED treatment. ED can be caused by the lack of blood flow into the penis, which Cialis can remedy. However, ED can also be caused by a low libido, which is more commonly due to improper hormone levels in the body, most commonly low testosterone. If a hormone problem exists yet blood flow is fine, Cialis will not remedy the ED issue nor will any PED5 medication. However, while it will remedy a blood flow issue, there are many men who need both issues addressed, blood flow and hormone.
The effects of Cialis have also been used to treat high blood pressure in some cases as the medication will lower blood pressure; in fact, in 2009 Cialis was approved for the treatment of pulmonary arterial hypertension. In 2011 it was then approved for the treatment of BPH as it was shown to reduce pressure around the prostate and urinary tract.
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